Saint Artemius lived during the years of Saint Constantine the Great, and was appointed by him to be Governor of Alexandria; later, he was honoured with the rank of patrician. During the reign of Julian the Apostate, in the year 361, Artemius appeared before the Emperor and censured him for his apostasy. For this, he endured many torments and was finally beheaded.

Saint Gerasimus was from the Peloponnesus, the son of Demetrius and Kale, of the family of Notaras. He was reared in piety by them and studied the Sacred writings. He left his country and went throughout various lands, and finally came to Cephalonia, where he restored a certain old church and built a convent around it, where it stands to this day at the place called Omala. He finished the course of his life there in asceticism in the year 1570. His sacred relics, which remain incorrupt, are kept there for the sanctification of the faithful.

This Saint was born at Tabatha, near Gaza in Palestine, of pagan parents. Sent as a young man to Alexandria to be educated, he learned the Christian Faith and was baptized. While in Egypt he heard the fame of Saint Anthony the Great, and upon meeting that truly great man, the Father of monks, Saint Hilarion determined to devote himself also to the ascetical life. He returned to Gaza, when, he gave himself over to extreme fasting and unceasing prayer. Because of the miracles which he soon began to work, he found himself compelled by his growing renown to leave Gaza, to escape from the throngs of people coming to ask his prayers. In his journeys he visited Egypt, and came again with longing to the place where Saint Anthony had lived; but he was not able to remain in any one place for long, since despite all his attempts to conceal himself, the light of the grace that was in him could not be hid. After passing through Egypt and Libya, and sailing to Sicily, he came at last to Cyprus, where he ended the course of his life at the age of eighty, in the year 372.

According to some, this Saint was a son of Joseph the Betrothed, born of the wife that the latter had before he was betrothed to the Ever-virgin. Hence he was the brother of the Lord, Who was also thought to be the son of Joseph (Matt. 13: 55). But some say that he was a nephew of Joseph, and the son of his brother Cleopas, who was also called Alphaeus and Mary his wife, who was the first cousin of the Theotokos. But even according to this genealogy, he was still called, according to the idiom of the Scriptures, the Lord's brother because of their kinship.

This Iakovos is called the Less (Mark 15:40) by the Evangelists to distinguish him from Iakovos, the son of Zebedee, who was called the Great. He became the first Bishop of Jerusalem, elevated to this episcopal rank by the Apostles, according to Eusebius (Eccl. Hist., Book II: 23), and was called Obliah, that is, the Just, because of his great holiness and righteousness. Having ascended the crest of the Temple on the day of the Passover at the prompting of all, he bore testimony from there concerning his belief in Jesus, and he proclaimed with a great voice that Jesus sits at the right hand of the great power of God and shall come again upon the clouds of heaven. On hearing this testimony, many of those present cried, "Hosanna to the Son of David." But the Scribes and Pharisees cried, "So, even the just one hath been led astray," and at the command of Ananias the high priest, the Apostle was cast down headlong from thence, then was stoned, and while he prayed for his slayers, his head was crushed by the wooden club wielded by a certain scribe. The first of the Catholic (General) Epistles written to the Jews in the Diaspora who believed in Christ was written by this Iakovos.

Saint Demetrius was a Thessalonian, a most pious son of pious and noble parents, and a teacher of the Faith of Christ. When Maximian first came to Thessalonica in 290, he raised the Saint to the rank of Duke of Thessaly. But when it was discovered that the Saint was a Christian, he was arrested and kept bound in a bath-house. While the games were under way in the city, Maximian was a spectator there. A certain friend of his, a barbarian who was a notable wrestler, Lyaeus by name, waxing haughty because of the height and strength of his body, boasted in the stadium and challenged the citizens to a contest with him. All that fought with him were defeated. Seeing this, a certain youth named Nestor, aquaintance of Demetrius', came to the Saint in the bath-house and asked his blessing to fight Lyaeus single-handed. Receiving this blessing and sealing himself with the sign of the precious Cross, he presented himself in the stadium, and said, "O God of Demetrius, help me!" and straightway he engaged Lyaeus in combat and smote him with a mortal blow to the heart, leaving the former boaster lifeless upon the earth. Maximian was sorely grieved over this, and when he learned who was the cause of this defeat, he commanded straightway and Demetrius was pierced with lances while he was yet in the bath-house, As for Nestor, Maximian commanded that he be slain with his own sword.

The great earthquake commemorated here took place in 740, during the reign of Leo the Isaurian, the first of the Iconoclast emperors.